The assertion was made in the latest Syria travel warning issued by the State Department on Wednesday. It also mentions Islamic State [IS, formerly ISIS/ISIL].

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“Terrorist and other violent extremist groups including ISIS and Al-Qaeda linked Hayat Tahrir Al-Sham [dominated by Al-Qaeda affiliate Jabhat Al-Nusra, a designated Foreign Terrorist Organization], operate in Syria,” the travel warning reads.

"Tactics of ISIS, Hayat Tahrir al-Sham, and other violent extremist groups include the use of suicide bombers, kidnapping, small and heavy arms, improvised explosive devices, and chemical weapons,” it said.

Terror groups have targeted roadblocks, border crossings, government buildings and other public areas in major Syrian cities of Damascus, Aleppo, Hama, Daraa, Homs, Idlib, and Deir-ez-Zor, the State Department acknowledged.

Meanwhile, Russia’s Defense Ministry said a precedent had been set by Washington acknowledging that Al-Nusra linked terrorists use chemical weapons in Syria.

“This is the first official recognition by the State Department not only of the presence, but the very use of chemical weapons by Al-Nusra terrorists to carry out terrorist attacks, which we repeatedly warned about,” General Igor Konashenkov, spokesman for the ministry, commented on Friday.

Previously, the US military reported chemical attacks in Syria.  Last November, Colonel John Dorrian, a spokesman for the US-led coalition in Iraq, said it is “concerned about Islamic State’s use of chemical weapons.”

“[Islamic State] has used them in Iraq and Syria in the past, and we expect them to continue employing these types of weapons,” Dorrian said in an emailed statement to the New York Times. 

The military official said the terrorist group’s ability to stage chemical attacks is “rudimentary,” adding that US, Iraqi and other coalition forces are capable of dealing with the impact of these attacks, namely “rockets, mortar shells or artillery shells filled with chemical agents.”