A 16-year-old boy was arrested after allegedly stabbing two men, killing one, at the organisation's headquarters in Chatswood, shortly after midday.

The two victims were Church employees, according to police, and were taken to Royal North Shore Hospital, where one died from a wound in his neck.

Detective Chief Inspector Simon Jones said the teen had been asked to leave the Scientology premises.

"On being escorted down the roadway a knife was produced and with that knife he stabbed a 24-year-old who we believe to be a Taiwanese male in the neck," Detective Chief Inspector Jones said.

"He also caused some lacerations to an older gentleman also escorting him from the premises."

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