About 2,800 New York City residents are under quarantine to prevent the spread of the coronavirus — and some could face fines or jail time if they venture outside their homes, officials said Thursday.

“The powers that we have could involve the police,” city Health Commissioner Dr. Oxiris Barbot warned during a news conference at One Police Plaza.

The city’s Department of Health was monitoring 2,773 people in “home isolation” as of Thursday morning, according to an afternoon update from Mayor Bill de Blasio’s office.

Only two, husband-and-wife health care workers from Manhattan, were under a mandatory quarantine order imposed when she tested positive for coronavirus following the couple’s return from Iran last week.

But officials said the number of people confined to their homes — either voluntarily or under orders — would almost certainly rise amid the outbreak.

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